Journal Paper
  Journal Paper
1. Hsien-Kuo Chin, Mei-Chin Lu, Kai-Cheng Hsu, Mohamed El-Shazly, Tsen-Ni Tsai , Tzu-Yung Lin, Shou-Ping Shih, Tony Eight Lin, Zhi-Hong Wen, Yu-Chen S H Yang and Yi-Chang Liu*, “Exploration of anti-leukemic effect of soft coral-derived 13-acetoxysarcocrassolide: Induction of apoptosis via oxidative stress as a potent inhibitor of heat shock protein 90 and topoisomerase II,” The Kaohsiung journal of medical sciences., Vol.39, No.7, pp.718-731, July 2023. (2022 IF=3.300, Ranking=81/136=59.56%, Category=MEDICINE, RESEARCH & EXPERIMENTAL)((Co-first author))
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2. Zheng-Yu Lin, Kun-Ching Cheng, Huey-Jen Su, Chi-I Chang, Jue-Liang Hsu, Min-fen Hsu, Mei-Chin Lu* and Yun-Sheng Lin*, “13-EPI-9-DEACETYLXENICIN DERIVATIVES FROM A TAIWANESE SOFT CORAL Asterospicularia laurae AND TREIR CYTOTOXIC ACTIVITY,” Chemistry of Natural Compounds,, Vol.58, No.4, pp.659-668, August 2022. (2021 IF=0.800, Ranking=45/52=86.54%, Category=CHEMISTRY, ORGANIC)(Co-corresponding author)
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3. Shou-Ping Shih, Mei-Chin Lu, Mohamed El-Shazly, Yu-Hsuan Lin, Chun-Lin Chen*, Steve Sheng-Fa Yu* and Yi-Chang Liu*, “The Antileukemic and Anti-Prostatic Effect of Aeroplysinin-1 Is Mediated through ROS-Induced Apoptosis via NOX Activation and Inhibition of HIF-1α Activity,” Life, Vol.12, No.5, pp.687-3.251, May 2022. (2022 IF=3.200, Ranking=46/111=41.44%, Category=BIOLOGY, Time Cited=11)
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4. Hung-Yu Lin, Yong-Shiou Lin, Shou-Ping Shih, Sung-Bau Lee, Mohamed El-Shazly, Ken-Ming Chang, Yu-Chen S H Yang, Yi-Lun Lee and Mei-Chin Lu*, “Anti-Proliferative Activity of Secondary Metabolite from the Marine Streptomyces sp. against Prostate Cancer Cells,” Life (Basel), Vol.11, No.12, pp.1414, December 2021. (SCI, 2022 IF=3.251, Ranking=39/94=41.49%, Category=BIOLOGY, Time Cited=11)
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5. Kuan-Chih Wang, Mei-Chin Lu, Kai-Cheng Hsu, Mohamed El-Shazly, Shou-Ping Shih, Ssu-Ting Lien, Fu-Wen Kuo, Shyh-Chyun Yang*, Chun-Lin Chen* and Yu-Chen S H Yang, “The Antileukemic Effect of Xestoquinone, A Marine-Derived Polycyclic Quinone-Type Metabolite, Is Mediated through ROS-Induced Inhibition of HSP-90,” Molecules, Vol.26, No.22, pp.7037, November 2021. (2022 IF=4.600, Ranking=97/285=34.04%, Category=BIOCHEMISTRY & MOLECULAR BIOLOGY, Time Cited=5)
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6. Kuei-Hung Lai, Bo-Rong Peng, Yu-Ming Hsu, Mohamed El-Shazly, Ying-Chi Du, Mei-Chin Lu, Jui-Hsin Su* and Yi-Chang Liu*, “The Configuration- Dependent Anti-Leukemic Effect of Manoalide Stereoisomers: Reignite Research Interest in these Sponge-Derived Sesterterpenoids,” Bioorganic chemistry, Vol.114, pp.105150, September 2021. (2022 IF=5.100, Ranking=7/52=13.46%, Category=CHEMISTRY, ORGANIC, Time Cited=4)
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7. Jui-Hsin Su, Chih-I Liu, Mei-Chin Lu, Chi-I Chang, Min-Ying Hsieh, Yu-Chi Lin, Chang-Feng Dai, Ya-Han Zhang, Zheng-Yu Lin and Yun-Sheng Lin*, “New secondary metabolite with cytotoxicity from spawning soft coral Asterospicularia laurae in Taiwan,” Natural product research, Vol.35, No.6, pp.967-975, March 2021. (2022 IF=2.200, Ranking=40/72=55.56%, Category=CHEMISTRY, APPLIED, Time Cited=9)
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8. Wen-Tsan Chang, Yung-Ding Bow, Pei-Jung Fu, Chia-Yang Li, Chang-Yi Wu, Yi-Hua Chang, Yen-Ni Teng, Ruei-Nian Li, Mei-Chin Lu, Yi-Chang Liu* and Chien-Chih Chiu*, “A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways,” Oxidative medicine and cellular longevity, Vol.2021, pp.7689045, January 2021. (2021 IF=7.310, Ranking=55/194=28.35%, Category=CELL BIOLOGY, Time Cited=78)
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9. Yi-Chang Liu, Bo-Rong Peng, Kai-Cheng Hsu, Mohamed El-Shazly, Shou-Ping Shih, Tony Eight Lin, Fu-Wen Kuo, Yi-Cheng Chou, Hung-Yu Lin* and Mei-Chin Lu*, “13-Acetoxysarcocrassolide Exhibits Cytotoxic Activity against Oral Cancer Cells through the Interruption of the Keap1/Nrf2/p62/SQSTM1 Pathway: The Need to Move Beyond Classical Concepts.,” Marine drugs, Vol.18, No.8, pp.382, August 2020. (2022 IF=5.400, Ranking=51/277=18.41%, Category=PHARMACOLOGY & PHARMACY, Time Cited=21)
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10. Bo-Rong Peng, Kuei-Hung Lai, You-Ying Chen, Jui-Hsin Su, Yusheng M Huang, Yu-Hsin Chen, Mei-Chin Lu, Steve Sheng-Fa Yu, Chang-Yih Duh and Ping-Jyun Sung, “Probing Anti-Proliferative 24-Homoscalaranes from a Sponge Lendenfeldia sp.,” Marine Drugs, Vol.18, No.2, pp.76, January 2020. (2022 IF=5.400, Ranking=51/277=18.41%, Category=PHARMACOLOGY & PHARMACY)
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11. Kuan-Chih Wang, Yi-Chang Liu, Mohamed El-Shazly, Shou-Ping Shih, Ying-Chi Du, Yu-Ming Hsu, Hung-Yu Lin, Yu-Cheng Chen, Yang-Chang Wu, Shyh-Chyun Yang and Mei-Chin Lu*, “ The Antioxidant from Ethanolic Extract of Rosa cymosa Fruits Activates Phosphatase and Tensin Homolog in vitro and in vivo: A New Insight on its Anti-Leukemic effect.,” International Journal of Molecular Sciences, Vol.20, No.8, pp.E1935, April 2019. (2022 IF=5.600, Ranking=66/285=23.16%, Category=BIOCHEMISTRY & MOLECULAR BIOLOGY, Time Cited=21)
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12. Chih-Fung Wu, Man-Gang Lee, Mohamed El-Shazly, Kuei-Hung Lai, Seng-Chung Ke, Chiang-Wen Su, Shou-Ping Shih, Ping-Jyun Sung, Ming-Chang Hong, Zhi-Hong Wen and Mei-Chin Lu*, “ Isoaaptamine Induces T-47D Cells Apoptosis and Autophagy via Oxidative Stress. ,” Marine Drugs, Vol.16, No.1, pp.pii:E18, January 2019. (2022 IF=5.400, Ranking=51/277=18.41%, Category=PHARMACOLOGY & PHARMACY, Time Cited=37)
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13. Yu-Cheng Chen, Mei-Chin Lu, Mohamed El-Shazly, Kuei-Hung Lai, Tung-Ying Wu, Yu-Ming Hsu, Yi-Lun Lee and Yi-Chang Liu*, “Breaking down Leukemia Walls: Heteronemin, a Sesterterpene Derivative, Induces Apoptosis in Leukemia Molt4 Cells through Oxidative Stress, Mitochondrial Dysfunction and Induction of Talin Expression,” Marine Drugs, Vol.16, No.6, pp.E212, June 2018. (2022 IF=5.400, Ranking=51/277=18.41%, Category=PHARMACOLOGY & PHARMACY, Time Cited=24)
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14. Man-Gang Lee, Yi-Chang Liu, Yi-Lun Lee, Mohamed EI-SHazly, Kuei-Hung Lai, Shou-Ping Shih, Seng-Chung Ke, Ming-Chang Hong, Ying-Chi Du, Juan-Cheng Yang, Ping-Jyun Sung, Zhi-Hong Wen and Mei-Chin Lu*, “Heteronemin, a Marine Sesterterpenoid-Type Metabolite, Induces Apoptosis in Prostate LNcap Cells via Oxidative and ER Stress Combined with the Inhibition of Topoisomerase II and Hsp90,” Marine Drugs, Vol.16, No.6, pp.pii:E204, June 2018. (2021 IF=5.400, Ranking=51/277=18.41%, Category=PHARMACOLOGY & PHARMACY, Time Cited=44)
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15. Mei-Chin Lu, Kuei-Hung Lai, Ying-Chi Du, Mohamed El-Shazly, Tung-Ying Wu, Yu-Ming Hsu, Astrid Henz, Juan-Cheng Yang, Anders Backlund, Fang-Rong Chang and Yang-Chang Wu, “Cytotoxic Lanostanoids from Poria cocos,,” Journal of Natural Products, Vol.79, No.11, pp.2805-2813, November 2016. (SCI, 2022 IF=5.100, Ranking=57/277=20.58%, Category=PHARMACOLOGY & PHARMACY, Time Cited=35)((共同第一作者))
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16. Kuei-Hung Lai, Yi-Chang Liu, Jui-Hsin Su, Mohamed El-Shazly, Chih-Fung Wu, Ying-Chi Du, Yu-Ming Hsu, Juan-Cheng Yang, Ming-Kai Weng, Chia-Hua Chou, Guan-Yu Chen, Yu-Cheng Chen and Mei-Chin Lu*, “Antileukemic Scalarane Sesterterpenoids and Meroditerpenoid from Carteriospongia (Phyllospongia) sp.Induce Apoptosis via Dual Inhibitory Effects on Topoisomerase II and Hsp90,” Scientific Reports, Vol.6, No.36170, pp.1-14, October 2016. (SCI, 2022 IF=4.600, Ranking=21/133=15.79%, Category=MULTIDISCIPLINARY SCIENCES, Time Cited=39)(通訊作者)
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Conference Paper
  Conference Paper
1. Hung-Yu Lin, Tsen-Ni Tsai, Min-Hung Shih, Lin-Chien Chiang, Shou-Ping Shih, Mohamed El-Shazly, Mei-Chin Lu* and Yi-Chang Liu, “Anti-prostate cancer mechanism of marine coral extract from Lobophytum crassum,” The 37th Symposium on Natural Products & the ceremony in Honor of Late Academicain Professor Kuo-Hsiung Lee, 高雄, Taiwan, October 21-23, 2022.
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Books
  Books
1. 張東柱、 吳永昌、 張芳榮、 陳介甫、 呂美津、 王隆耀、 蔡東榮、 蔣文欽、 杜英齊、 洪志昇、 吳東穎、 Mohamed El-Shazly、 許育銘、 賴奎宏、 邱錦朋、 鄭富庭、 何孟琦 , (2015年11月發行)《新圖解牛樟菇》, ISBN:978-986-91187-5-0 (平裝), 臺灣 台北:活石文化事業有限公司。

Articles
  Articles

Patents
  Patents
1. Mei-Chin Lu, Ping-Jyun Sung, Jui-Hsin Su, Kuei-Hung Lai, Yi-Chang Liu, Ying-Chi Du, Yu-Ming Hsu, Ming-Kai Weng and Fu-Wen Kuo, “Scalarane Sesterterpenoid, Pharmaceutical Composition and Topoisomerase II and HSP90 inhibitor for cancer, and use and preparation method thereof,” United States of America Patent US10,314,847 B2, June 11, 2019.
2. 呂美津, 宋秉鈞, 蘇瑞欣, 賴奎宏, 劉益昌, 杜英齊, 許育銘, 翁明楷 and 郭富雯, “來自Carteriospongia (Phyllospongia) sp.的抗血癌Scalarane Sesterterpenoids及Meroditerpenoid經由對拓樸異構酶II及Hsp90的雙重抑制效果誘導細胞凋亡,” Taiwan Patent 發明第I651088號, February 21, 2019.
3. 呂美津、宋秉鈞、蘇瑞欣、賴奎宏、劉益昌、杜英齊、許育銘 和 郭富雯, 〈Manoalide衍生物異構物的分離及鑑定、以及其構型依賴抗血癌與抗淋巴癌功效〉 臺灣專利 發明第I642665號, 2018年十二月1日。

Show
  Show

Reports
  Reports

Lectures
  Lectures